Nanocrystals - from fast dissolution and improved solubility to controlled release applications

02 July 2014 in Research Highlights 561 hits

Problems related to low oral bioavailability due to poor solubility of new drug candidates are an increasing challenge in pharmaceutical…

Injection Molding as an Hot Melt Extrusion Downstream Process

28 May 2014 in Research Highlights 1128 hits

Introduction Over the last years, hot melt extrusion (HME) has attracted significant interest in the pharmaceutical industry. HME is performed…

Taste-Masking for Paediatric Medicines

15 November 2013 in Research Highlights 3934 hits

Introduction Following the implantation of European regulation with respect to medicinal products for paediatric use, scientist community has to speed…

Classification and quantification of API in counterfeit pharmaceuticals via Raman spectroscopy

10 November 2013 in Research Highlights 4889 hits

Background Counterfeit medicines have become an increasing issue worldwide, affecting both developing and developed countries. The presence of counterfeit medicines…

Surface characterization of solid dispersions

07 September 2013 in Research Highlights 5314 hits

Background Solid dispersions are an intensively investigated enabling technology to formulate poorly soluble drugs. Many contributions already studied their higher…

Influence of Compression forces on the Physical and Structural Stability of Solid Dispersions

03 July 2013 in Research Highlights 12670 hits

Background The structural and physical stability of solid dispersions have not been adequately explored during post spray drying manufacturing processes.…

Non-linear optical imaging of solid drugs and dosage forms

19 June 2013 in Research Highlights 8100 hits

Non-linear Optical Imaging Non-linear optical imaging is an emerging technique for imaging drugs and dosage forms [1]. Non-linear optical imaging…

Pellet Production by Hot Melt Extrusion and Die Face Pelletising

07 May 2013 in Research Highlights 7208 hits

Introduction The production and manufacturing of solid pharmaceutical products is in need of new technologies to ensure a safe and…

Understanding Continuous High Shear Wet Granulation in Pharmaceutical Production

15 April 2013 in Research Highlights 16703 hits

Introduction Continuous processing is a promising approach for solid dosage manufacturing. High-shear wet granulation is performed in continuous mode using…