Background Poly(lactic-co-glycolic acid) (PLGA)-based microparticles offer a great potential as parenteral controlled drug delivery systems [1]. Different types of drug…

The potential of amorphous solid dispersions to improve the solubility, dissolution rate and bioavailability of poorly water soluble drugs is…

For the first time, an appropriate solid dosage form was developed for a co-amorphous drug-amino acid formulation, demonstrating the high…

We have developed a new technique to better understand what happens to the microstructure inside a tablet during rapid disintegration.

Background Terahertz pulsed imaging (TPI) was first introduced in 2007 to non-destructively measure the coating thickness of pharmaceutical tablets. Ever…

Background The mechanism of plastic deformation in amorphous polymers is still obscure due to lack of experimental techniques to probe…

Problems related to low oral bioavailability due to poor solubility of new drug candidates are an increasing challenge in pharmaceutical…

Introduction Over the last years, hot melt extrusion (HME) has attracted significant interest in the pharmaceutical industry. HME is performed…

Introduction Following the implantation of European regulation with respect to medicinal products for paediatric use, scientist community has to speed…