Influence of the Suspension Composition on the Mechanical Strength of Dried Microspheres

10 September 2018 in Research Highlights 582 hits

Spray drying is widely used in pharmaceutical manufacturing to produce microspheres from solutions or suspensions. The mechanical properties of the…

Novel stand-alone test tool for scientific qualification of a dosator capsule filling process

10 September 2018 in Research Highlights 563 hits

One of the biggest problems in the manufacturing of high-quality low-dose inhalation products, is dose uniformity of filled capsules [1].…

Modeling Powder Compaction using a Multi-Particle Finite Element Model

10 September 2018 in Research Highlights 883 hits

1. Introduction Cold compaction of powder is important for many industrial processes, e.g., for the production of green bodies before…

Control performance of different roll compactors

22 December 2016 in Research Highlights 13078 hits

Written by Kitti Csordas, early stage researcher in the IPROCOM project

Does PLGA microparticle swelling control drug release?

26 January 2016 in Research Highlights 19593 hits

Background Poly(lactic-co-glycolic acid) (PLGA)-based microparticles offer a great potential as parenteral controlled drug delivery systems [1]. Different types of drug…

Ensuring thermodynamic stability of amorphous solid dispersions by predicting drug-polymer solubility

25 November 2015 in Research Highlights 24341 hits

The potential of amorphous solid dispersions to improve the solubility, dissolution rate and bioavailability of poorly water soluble drugs is…

Downstream processing of a co-amorphous drug-amino acid formulation

18 November 2015 in Research Highlights 17833 hits

For the first time, an appropriate solid dosage form was developed for a co-amorphous drug-amino acid formulation, demonstrating the high…

Beyond Traditional Disintegration Testing

17 June 2015 in Research Highlights 25509 hits

We have developed a new technique to better understand what happens to the microstructure inside a tablet during rapid disintegration.