University of Helsinki has an opening for a 18-month PostDoc position in ultrasensitive analytical technologies of advanced pharmaceutical systems. This position is part of a project that aims for successful development of dosage forms based on solid dispersions combining new/state-of-the-art solid dispersion production and ultra-sensitive analytical technologies. The appointee will perform research on the novel analytical characterization of the solid dispersions and biorelevant performance testing. We are looking for a person with a PhD degree in chemistry or other relevant background with expertise in analytics, especially in spectroscopic methods (FTIR, Raman, UV/Vis) and in XRPD and DSC. More information can…
Thursday, 19 September 2019 08:45

13th PSSRC Annual Meeting at the HHU

The annual meeting in Duesseldorf
Thursday, 08 November 2018 13:03

12th PSSRC Meeting in Leuven in Belgium

The twelfth annual meeting of the Pharmaceutical Solid State Research Cluster was held in Leuven (University of Leuven, KU Leuven) from 12 to 14 September 2018. It was attended by 122 participants (91 during the closed days and 31 during the open day) from the member research groups and alumni across Europe.
A new method for measuring of molecular mobility in glassy materials has been developed using terahertz spectroscopy. The absorption level of amorphous drugs at terahertz frequencies below Tg correlates with the stability of the drug as an amorphous solid. The molecular mobility responsible for the glass crystallisation significantly decreases at around a universal value of 0.67 Tg. This explains why the commonly used rules of thumb for glasses to remain stable below 0.8 Tg or Tg – 20 K do not work reliably. These results reveal a unique and completely novel opportunity to predict and test the stability of amorphous…